A new pharmacologic approach to safer opioid pain management
Lower doses. Reduced reward. Reduced tolerance. Pain relief maintained.
The mission-critical need
Effective pain relief should not require unnecessary risk
Acute pain is common after surgery, trauma, and injury. Opioids remain an essential option when effective analgesia is required, including for service members, veterans, and civilian patients.
Conventional opioids can cause sedation, cognitive impairment, tolerance, and reward-driven misuse risks that may complicate recovery, rehabilitation, and return to function.
Amalgent is developing a fixed-dose combination designed to preserve analgesia while enabling lower opioid exposure and addressing the neurobiology of opioid reward.
